All functions

Celegans_TS_data

RNAseq counts for Celegans and krill oil timeseries exeriment time series experiment

DE_plots_vignettes()

Creates differential expression results for Vignettes

DE_using_DESeq2()

DE with DESeq2

DE_using_limma()

DE using limma

GO_dotplot_wrapper()

Create gprofiler dotplots

PART_heat_map()

Create and plot PART heatmap

PBMC_TS_data

RNAseq counts for AID activation cocktail in PBMC time series experiment

PBMC_pre_loaded

Pre-computed PART and gprofiler results for the PBMC dataset

PartRec()

PartRec

SS_GO_clusters()

Find semantic similarity between clustered GOs

TS_load_example_data()

Add counts and sample data of examples to a TimeSeriesObject

TimeSeries_Object-class TimeSeries_Object

The TimeSeries class

add_exp_data_tximport()

Adds experiment data from tximport estimated reads in the form of a SummarizedExperiment

add_experiment_data()

Adds experiment data in the form of a SummarizedExperiment

add_semantic_similarity_data()

Calculate and add semantic similarity to object

calculate_EB()

Empirical bayesan analysis

calculate_and_format_MDS()

Calculate MDS matrix

calculate_cluster_traj_data()

Calcualte trajectory of clusters

calculate_gene_traj_data()

Calculate trajectory of a single gene

calculate_mean_cluster_traj()

Calculate mean trajectory of clusters

celegans_pre_loaded

Pre-computed PART and gprofiler results for the PBMC dataset

compute_PART()

compute PART clusters

conditional_DE_wrapper()

Create conditional DE results

convert_eb_res_to_DE_results()

Format limma DE results

create_DEG_df()

Create summary table for DEGs

create_DE_data_results()

Create and save DE results

create_clustered_module_dataframe()

Format clustered GO data for plotting

create_conditional_heatmap_matrix()

Create data for conditional heatmap

create_example_data_for_R()

Create a subset of count data for R examples (documentation)

create_example_object_for_R()

Create a TimeSeries_Object from example data

create_raw_count_matrix()

Prep TS matrix

create_tables_genes_of_interest_DE()

Creates tables and plots for genes of interest

create_temporal_heatmap_matrix()

Create data for temporal heatmap

custom_gpro_dotplot()

Create dotplot for gprofiler results

custom_heatmap_wrapper()

Create heatmap for differential gene expression results

doHclust()

doHclust

doKmeans()

doKmeans

dotplot_ancestors()

Create dotplot for ancestor query results

exp_matrix()

Fetches a data matrix from summarized experiments

exp_sample_data()

Fetches the sample data

findPartition()

findPartition

findW()

findW

find_clusters_from_termdist()

Cluster GO terms using Wang measurement

find_merged_color()

associate color to group for plotting

find_most_variable_cluster()

Identify cluster with the most variability

find_relation_to_ancestors()

Ancestor querying for GOs

gap()

gap

get.threshold()

get.threshold

getDist()

getDist

getPARTlabels()

getPARTlabels

getReferenceW()

getReferenceW

gprofiler_cluster_analysis()

Plot gprofiler results

identify_problematic_combs()

Identify and remove bad combs

log_transform_l2fc_vect()

Log transform L2FC/FC values

maplot_alt()

Create an MA plot

merge_duplicate_modules()

merge_MDS modules

murine_TS_data

RNAseq counts for AID activation cocktail in a murine timeseries exeriment time series experiment

murine_pre_loaded

Pre-computed PART and gprofiler results for the PBMC dataset

normalize_timeSeries_with_deseq2()

Normalize with DESeq2

part()

part

part_gprofiler_vignettes()

Gprofiler analysis for Vignettes

part_load_results_vignettes()

PART analysis for Vignettes

plot_MDS()

Create MDS plot

plot_PCA_TS()

Plot timeseries PCA

plot_ancestor_clust_MDS()

Plot nearest ancestor MDS (clustered GOs)

plot_cluster_traj()

Plot cluster trajectories

plot_clustered_mds()

plot clustered MDS

plot_custom_DE_heatmap()

Plots DE heatmaps

plot_gene_traj_single_tp()

Calculate trajectory of a single gene with no timepoints

plot_single_gene_traj()

Plot gene trajectory

plot_wrapper_DE_results()

Creates differential expression results

prep_RNAseq_matrix()

prep count matrix form RNAseq count files

prep_counts_for_PART()

Format data for PART

prep_limma_matrix()

Prepare data matrix from a Elist object

prep_sample_data()

Sample data set-up

prep_tp_matrix()

limma timepoint matrix

prepare_heat_data()

Process data for DE heatmap

prepare_top_annotation_PART_heat()

Create top annotation for PART heatmap

process_microarr_dta_limma()

Read and process microarray data using the limma package

read_gprofiler_results()

Read gprofiler data from results folder

run_gprofiler_PART_clusters()

Gprofiler analysis

select_genes_with_l2fc()

Select genes based on L2FC/FC

sim()

sim

temporal_DE_wrapper()

Create temporal DE results

volcanoplot_alt()

Create a volcano plot

wrapper_MDS_and_MDS_clusters()

Create MDS and nearest ancestor MDS plots

wrapper_ancestor_curation_plots()

Create ancestor query plots

wrapper_cluster_trajectory()

Plot cluster trajectory for all PART clusters

write_example_data_to_dir()

Prep example data in directory